Biopsja mammotomiczna w diagnostyce niepalpacyjnych zmian patologicznych piersi

Background: The aim of the study was to determine the effectiveness of mammotome biopsy (MB) in detecting preclinical breast pathologies. Material/Methods: The material consisted of 847 women, of whom, based on mammography and ultrasound, 349 patients were referred to have stereotactic mammotome biopsy (SMB) guided by digital mammography and 498 women were subjected to hand-held mammotome biopsy (HHMB) guided by US. Results: Ultimately, MB was done in 819 women. In all cases where breast carcinoma or atypical ductal hyperplasia (ADH) were detected, the patients were operated on and postoperative histopathology was treated as the reference for post-biopsy histopathology. Patients in whom post-MB histopathology detected benign lesions were subjected to a strict long-term follow-up using imaging studies. Ultimately, thanks to MB, 94 cases of breast cancer (12%) were detected as well as 725 (88%) cases of benign lesions, which corresponds to a sensitivity of 98.9% and 100% specificity. Conclusions: MB is an alternative to surgical biopsy in differentiating preclinical breast lesions. It is associated with a minimal risk of complications and may be successfully performed in an outpatient setting

Core breast biopsy under MR control : preliminary results

Background: Breast MR examination is capable of detecting suspected lesions that are not visualized by other imaging techniques, such as mammography or ultrasonography. In all cases such lesions should be verified histopathologically by MR-guided core biopsy. The aim of the study was the determination of effectiveness of MR-guided breast core biopsy in detection of breast pathologies. Material/Methods: Twelve women with suspected lesions detected by MR (GEMS Signa Excite 1.5 T with 4-channel open breast coil manufactured by MRI Devices Corporation) were qualified to MR-guided breast biopsy. Obtained image data were transferred to DYNACAD workstation for calibration, lesion localization, and automatic calculation of target coordinates for MR-guided intervention. Biopsy was performed using automated 14G biopsy needle. Results: MR-guided breast biopsy was performed in 9 women and confirmed lobular and ductal carcinoma in 2 patients respectively, lobular carcinoma in situ (LCIS) in 1, intraductal papilloma in 2, and intraductal hyperplasia without atypia. In 3 patients histopathologic examination revealed benign fibrocystic lesions. Three women were disqualified from biopsy because pre-biopsy MR sequences did not reveal the lesion in 1 case, and due to the target localization out of reach of the biopsy needle in other 2 cases. Conclusions: All non-palpable lesions visualized by MR (contrast-enhanced signal in dynamic examination) should be verified by MR-guided breast biopsy. In each case histopathologi

A Case of Extensive Infl ammatory Changes (Osteomyelitis) in an Infant’s Skeleton from the Medieval Burial Ground (11th–12th c) in Wawrzeńczyce (Near Krakow)

The aim of this study was to diagnose and describe extensive infl ammatory changes in a child’s skeleton from Wawrzeńczyce, (the medieval period). The aim of the analysis was to determine the nature of the infl ammatory changes and their etiology by means of macroscopic techniques as well as X-ray analysis. The tests revealed that the individual suffered from a hematogenous multifocal osteitis. This condition might have been a result of an acute or sub-acute osteitis, and the untreated form of osteomyelitis might have contributed to the infection of the entire developing organism, leading to death

A Case of Extensive Infl ammatory Changes (Osteomyelitis) in an Infant’s Skeleton from the Medieval Burial Ground (11th–12th c) in Wawrzeńczyce (Near Krakow)

The aim of this study was to diagnose and describe extensive infl ammatory changes in a child’s skeleton from Wawrzeńczyce, (the medieval period). The aim of the analysis was to determine the nature of the infl ammatory changes and their etiology by means of macroscopic techniques as well as X-ray analysis. The tests revealed that the individual suffered from a hematogenous multifocal osteitis. This condition might have been a result of an acute or sub-acute osteitis, and the untreated form of osteomyelitis might have contributed to the infection of the entire developing organism, leading to death

Slučaj ekstenzivnih upalnih promjena kostura dojenčadi (osteomijelitis) sa slučaj ekstenzivnih upalnih promjena kostura dojenčadi (osteomijelitis) sa srednjovjekovnog groblja (11.-12. St.) u Wawrzeńczycama (blizu Krakowa)

The aim of this study was to diagnose and describe extensive infl ammatory changes in a child’s skeleton from Wawrzeńczyce, (the medieval period). The aim of the analysis was to determine the nature of the infl ammatory changes and their etiology by means of macroscopic techniques as well as X-ray analysis. The tests revealed that the individual suffered from a hematogenous multifocal osteitis. This condition might have been a result of an acute or sub-acute osteitis, and the untreated form of osteomyelitis might have contributed to the infection of the entire developing organism, leading to death.Cilj ovog istraživanja bio je dijagnosticirati i opisati ekstenzivne upalne promjene u djetetovu kosturu iz Wawrzeńczyce, (period srednjega vijeka). Cilj analize bio je utvrditi prirodu upalnih promjena i njihovu etiologiju pomoću makroskopskih tehnika, kao i X-zraka. Testovi su pokazali da je pojedinac patio od hematogenog multifokalnog ostitisa. Takvo je stanje moglo biti posljedica akutnog ili subakutnog ostitisa, a ne tretirani oblik osteomijelitisa mogao je pridonijeti infekciji cijelog organizma u razvoju, što je dovelo do smrti